You might want to put more effort in your character designs, I got the main character confused with the new guy quite often. If I put your two human characters in a crowd of other artists' characters they would not stand out.
Defining characters can be as simple as just color coding your characters, like the Power Rangers or Sonic; to designing a character with features that are not too common like Mickey Mouse's round ears or Pikachu's lightening bolt tail.
The story was simple but the goal was unclear, you also might want introduce the goal near the beginning of the story, I couldn't even tell if the main character wanted to avoid Damien until I read the description. But without a goal a story becomes scrambled and unconnected.
The special effects were uh not too good, I learned effects by simply looking at video game pixel art sprite sheets online, and by just drawing and animating fire lightening etc in YouTube videos. Better lip syncing will bump up the quality and so will some backgrounds too.
But it's pretty entertaining just how it is though. It's pretty funny.
And at least there's some conflict and character flaws which are crucial.
It's antisocial characters, brashness, and randomness reminds me of Erick the Juiceman. Way to go!